Donald R. Nixdorf, DDS, MS

Dr. Nixdorf is a Professor and Director of the Division of TMD & Orofacial Pain. His clinical and teaching interests include the diagnosis and management of chronic TMD pain, headaches and neuropathic pain. His research is focused on the topic of persistent non-odontogenic “tooth” pain, looking at issues related to classification (e.g., consensus building), diagnosis (e.g., development of criteria, imaging, screening questionnaires), epidemiology, (e.g., determining predictive factors, assessing of impact), exploration of mechanisms (e.g., sensory testing, functional imaging), and treatment options.

• 2018 Honorary Membership in the American Association of Endodontists (AAE)
• 2017 Clinical Paper of the Year, School of Dentistry, University of Minnesota
• 2016 Clinical Paper of the Year, School of Dentistry, University of Minnesota
• 2015 AAE Foundation’s highest scoring faculty research grant proposal
• 2015 Journal of Endodontics award for best clinical research publication
• 2012 Alpha Omega dental society inductee
• 1998 Phi Kappa Phi honor society inductee
• 1998 Ohio State Post College Assembly table clinic award
• 1997 Biotene award, excellence in hospital dentistry
• 1995 Dentsply table clinic award
• 1995 Academic All Canadian
• 1995 & 1994 Jimmie Condon track and field scholarships
• 1994 & 1993 Farquarson research scholarships

2006 – present International & American Association for Dental Research

2002 – present American Academy of Orofacial Pain

2000 – present International Association for the Study of Pain

2003 – 2007 American, Minnesota & Minneapolis Dental Societies

2000 – 2007 American Headache Society

2004 – 2006 International Headache Society

2000 – 2006 Canadian Pain Society

1998 – 2014 American Dental Society of Anesthesiology

1999 – 2002 Canadian & Alberta Dental Association

Active

“Diagnostic accuracy of MRI to detect vertical root fractures in extracted endodontically treated teeth”
Study Goal: Determine the limit of fracture width detection with 80% sensitivity and compare the diagnostic accuracy between cone-beam CT with MRI when using microCT as the reference standard.
Role = co-I @ 2.5% effort (PI: Beth Morrey)
Funding Agency: American Academy of Orofacial Pain (AAOP)
Funding Duration: April 1, 2019 to March 31, 2021

“Ex vivo and In vivo Dental MRI Imaging of Blood Flow in Teeth”
Study Goal: Establish the lower limits of fluid flow detection in an ex vivo model then demonstrate feasible to detecting blood follow in teeth within in vivo environment.
Role = co-I @ 2.5% effort (PI: Lars Gaalaas)
Funding Agency: American Academy of Oral & Maxillofacial Radiology (AAOMR)
Funding Duration: March 15, 2018 to February 28, 2020

Completed

“Predictors of Endodontic Treatment Outcomes” U19-DE022516
Study Goal: Planning and implementation for a prospective observational study that will identify the predictive factors for severe acute pain and assess the impact of persistent pain over the course of 1-year follow of patients that received initial orthodgrade root canal therapy.
Role = Study PI @ 20% effort (PI: Gregg Gilbert)
Funding Agency: Subcontract from U19 grant application
Funding Duration: November 1, 2014 to March 31, 2019

“National Dental Practice-Based Research Network” U19-DE022516
Source: NIDCR
Study Goal: Develop The National Dental Practice-Based Research Network (NDPBRN) and conduct clinical research about, in, and for the benefit of “real world” everyday practicing oral health professionals.
Role = Deputy Director for Midwest Region @ 20% effort (PI: Gregg Gilbert)
Funding agency: NIH/NIDCR
Funding duration: April 1, 2012 to March 31, 2019

“Developing Dental Magnetic Resonance Imaging (MRI): Reliability Assessment of Detecting Cracks in Teeth”
Study Goal: Derive MRI criteria for crack identification in teeth, establish the reliability, and demonstrate it is feasible to detect such cracks in vivo. This will be accomplished by consensus building and reiterative changes to the criteria, obtaining MRIs of ex vivo teeth/jaw specimens (with before and after comparison), and imaging 5 patients with known cracked teeth.
Role = PI @ 2.5% effort
Funding Agency: American Association Endodontic (AAE) Foundation
Funding Duration: April 1, 2016 to March 31, 2018

“SWIFT MRI for evaluation of mandibular invasion in oral squamous cell carcinoma”
Study Goal: Develop a SWIFT compatible MRI coil to image the bone-soft tissue interface to assess for penetration prior to surgical exploration.
Role = content expert (PI: Samir Khariwala)
Funding Agency: UMN CTSI’s Novel Methods pilot opportunity
Funding Duration: September 1, 2012 to August 31, 2014

“Understanding the impacts of persistent tooth pain”
Study Goal: Using qualitative data collection methods, describe the impacts of this pain has of people's daily life.
Role = PI & Faculty supervisor (Fellow: Justin Durham)
Funding agency: SOD Lasby Visiting Fellowship, University of Minnesota
Funding Duration: July 1, 2012 to June 30, 2014
Supplement to P41-RR008079 “NMR Imaging & Spectroscopy”

“Development of Dental Magnetic Resonance Imaging using SWIFT”
Study Goal: Establish the feasibility of in vivo MR-imaging of both calcified and non-calcified tissues of teeth with a resolution 0.2 mm, in three-dimensions.
Role = Co-I at 20% effort (PI: Kamil Ugurbil)
Funding Agency = NIH/NCRR
Funding Duration: September 15, 2011 to March 31, 2013

“Diagnosis for persistent dentoalveolar pain following root canal therapy”
Study Goal: This is a nested case-control study that seeks to identify etiologic factors associated with patients who report pain at 6 months within DPBRN Study 18.
Role = PI @ 5% effort
Funding agency: AAE Foundation & AAOP
Funding Duration: July 1, 2011 to June 30, 2012
Dental Practice-Based Research Network (DPBRN) study protocols 17 & 18

“Peri-operative Pain and Root Canal Therapy”
Study Goal: Determine the frequency and magnitude of tooth pain present 1 week and 6 months following initial orthograde root canal therapy.
Role = Project Manager for both studies @ 40% effort (PI: Gregg Gilbert)
Funding agency: NIH/NIDCR
Status: Sub-contracts granted from U01-DE016747
Project duration: April 1, 2009 to March 31, 2012
Infrastructure Investment Initiative (I3) Award

“New Infrastructure for Campus-wide Access to 3T MRI”
Study Goal: Set up a second 3 Tesla MRI machine in CMMR to keep pace with current research demands of scanner time.
Role = Co-I (PI: Stephen Engle)
Funding agency: UMN, Office of Vice President Research
Project duration: June 1, 2011 to December 31, 2011
Scholar Development Clinical Research (RMI) (K12, CAPS)

“Functional Neuroimaging of Neuropathic Orofacial Pain: A pilot study”
Study Goal: Develop an intra-oral stimulus device that is MRI compatible, demonstrate feasible of imaging BOLD activity resultant from painful intra-oral stimulation, and perform group-wise comparison between subjects with neuropathic tooth pain compared to pain-free controls.
Role = Scholar @ 75% effort (PI: Russell Luepker)
Senior Mentor: Eric Schiffman
Supporting Mentors: David Bereiter, Noam Harel, Mike John, Kamil Ugurbil, Jim Hodges
Funding agency: NIH/NCRR, granted within K12-RR023247
Funding duration for Scholar: February 2007 to July 2010

“Cross-sectional Evaluation of Pain Cases and pain-Free Controls”
Study Goal: Determine whether there are differences in tasting ability between two different TMD pain patients groups compared to matched controls.
Role = Co-I on resident project (PI: Robert Utsman)
Funding agency: American Academic of Orofacial Pain (AAOP)

“Case series assessment of the effectiveness of methotrexate treatment for chronic pain after TMJ implant removal”
Study Goal: Investigate the effectiveness of methotrexate for reducing pain in patients who have persistent chronic temporomandibular joint (TMJ) pain after Silastic® or Proplast® implant placement and subsequent removal
Role = Principle Investigator @ 5% effort
Funding agency: University of Minnesota Oral Health Clinical Research Center
Project duration: October 2006 to June 2008
Investigational New Drug (IND) application with the FDA (#74,715)

“Quantitative Neurosensory Testing for TMD/Orofacial Pain Patients”
Study Goal: Evaluate the difference in pin-point pain threshold perception, pressure pain threshold perception and vibrotactile perception of pain in subjects with temporomandibular joint and masseter muscle pain compared to and pain-free participants.
Role: Principle Investigator @ 20% effort
Funding agency: University of Minnesota School of Dentistry
Project duration: September 2005 to October 2006

“Comprehensive Training in Inter-Disciplinary Oral Health Research”
Study Goal: Comprehensive training in interdisciplinary oral health research for dental faculty that covers a broad spectrum of interdisciplinary oral health research areas.
Role: Scholar @ 100% effort (PI: Tim DeRouen)
Funding agency: NIDCR, T32-DE71222 - Ruth L. Kirschstein Research Service Award
Project duration: June to September 2005

“Teledentistry Project: Increasing Rural Access to Dental Specialists”
Study Goal: Provide TMD, orofacial pain and oral medicine care to rural Minnesota practitioners via telehealth technology.
Role: Co-investigator @ 1% effort (PI: James Fricton)
Funding agency: Minnesota Department of Education
Project duration: November 2004 to October 2006, except June to September 2005

“NIDCR’s TMJ Implant Registry and Repository (TIRR)”
Study Goal: Collect clinical information and biological specimens from patients with TMD disorders throughout the United States to stimulate research on TMJ implants
Role: Co-investigator @ 2% effort (PI: James Fricton)
Funding agency: NIDCR, N01-DE22635
Funding duration: September 2005 to January 2007

“Randomized controlled trial of botulinum toxin A for masticatory myalgia”
Study Goal: Pilot study to assess the effectiveness of botulinum toxin A for myalgia pain in TMD subjects
Role: Principle Investigator @ 60% effort
Funding agency: University of Alberta Fund for Dentistry, Allergan Inc. & McNeil Pharmaceuticals
Project duration: January 2000 to June 2002

U.S. Patent number: US 9,541,615 B2

System and Method for Multi-ROI MRI Imaging using an RF Loop Coil

Status: awarded January 10, 2017

Peer-Review Articles

Coulter J, Nixdorf DR. A review of persistent idiopathic dentoalveolar pain (formerly PDAP/Atypical odontalgia). Submitted to Oral Surgery for publication consideration

Herrero Babiloni A, Nixdorf DR, Moana-Filho EJ. Persistent dentoalveolar pain disorder: a putative intraoral chronic overlapping pain condition. Submitted to Oral Diseases for publication consideration

Sude A, Nixdorf DR. Prevalence and clinic characteristics of oromandibular dystonia patients in orofacial pain clinic: A retrospective study. Submitted to JADA for publication consideration

Sude A, Nixdorf DR, Grande A. HPV positive oropharyngeal squamous cell carcinoma presenting as glossopharyngeal neuralgia. Submitted to JADA for publication consideration

Sharma S, Breckon M, Bronnimann Lambelet B, Chung JW, List T, Lobbezoo F, Nixdorf DR, Oyarzo J F, Peck C, Tsukiyama Y, Ohrbach R. Challenges to implementation and utility of a biopsychosocial model for the assessment and management of orofacial pain. In press with Journal of Oral Rehabilitation

Schuurmans TJ, Nixdorf DR, Idiyatullin D, Law AS, Barsness BD, Roach SH, Gaalaas L. Accuracy and reliability of root crack and fracture detection in teeth using magnetic resonance imaging (MRI). Journal of Endodontics (June) 2019;45(6):750-755. PMID:31056300

Durham J, Stone SJ, Robinson LJ, Ohrbach R, Nixdorf DR. Developing and preliminary evaluation of a new screening instrument for atypical odontalgia and persistent dentoalveolar pain disorder. International Journal of Endodontics (March) 2019;52(3):279-287. PMID:30229950

Hryvenko I, Cervantes-Chavarria AR, Law AS, Nixdorf DR. Hemicrania continua: Case series presenting in an orofacial pain clinic. Cephalalgia (November) 2018;38(13)1950-1959. PMID:29562746

Herrero Babiloni A, Guay S, Nixdorf DR, de Beaumont L, Lavigne G. Non-invasive brain stimulation in chronic orofacial pain: a systematic review. Journal of Pain Research (August) 2018;11:1445-1457. PMCID:PMC6078189

Kaimal S, Ahmad M, Kang W, Nixdorf D, Schiffman EL. Diagnostic accuracy of panoramic radiography and MRI for detecting signs of TMJ degenerative joint disease. General Dentistry (July-August) 2018;66(4):34-40. PMID:29964246

Devine M, Hirami M, Durham J, Nixdorf DR, Renton T. Identifying criteria for diagnosis of post-traumatic pain and altered sensation of the maxillary and mandibular branches of the trigeminal nerve: a systematic review. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology (June) 2018;125(6):526-540. PMID:29426749

Moana-Filho EJ, Alonso AA, Kapos FP, Leon-Salazar V, Durand SH, Hodges JS, Nixdorf DR. Multifactorial assessment of measurement errors affecting intraoral quantitative sensory testing reliability. Scandinavian Journal of Pain (July) 2017;16:93-98. PMCID:PMC5598789

Cervantes Chavarria AR, Nixdorf DR. The patient you will never forget: PDAP. Northwest Dentistry (March-April) 2017;96(2):15-19. PMID:30549759

Herrero Babiloni A, Nixdorf DR, Law AS, Moana-Filho EJ, Shueb SS, Nguyen RH, Durham J. Initial accuracy assessment of the modified S-LANSS for the detection of neuropathic orofacial pain conditions. Quintessence International 2017;48(5):419-429. PMID:27981266

Al-Musawi M, Durham J, Whitworth JM, Stone SJ, Nixdorf DR, Valentine RA. Effect of topical neuromodulatory medications on oral and skin keratinocytes. Journal of Oral Pathology and Medicine (February) 2017;46(2):134-141. PMID:26991677

Fonseca Alonso B, Nixdorf DR, Shueb SS, John MT, Law AS, Durham J. Examining the sensitivity and specificity of two screening instruments: odontogenic or temporomandibular disorder pain? Journal of Endodontics (January) 2017;43(1):36-45. PMID:27986100

Durham J, Al-Baghdadi M, Baad-Hansen L, Breckons M, Goulet JP, Lobbezoo F, List T, Michelotti A, Nixdorf DR, Peck CC, Raphael K, Schiffman E, Steele JG, Story W, Ohrbach R. Self-management programmes in TMD: results from an international Delphi process. Journal of Oral Rehabilitation (December) 2016;43(12):929-936. PMID:27727477

Sun Y, Brauckmann O, Nixdorf DR, Kentgens A, Garwood M, Idiyatullin D, Heerschap A. Imaging human teeth by 31P MRI with Nuclear Overhauser Enhancement. Scientific Reports (August) 2016;6(30756):1-9. PMCID:PMC4976379

Idiyatullin D, Garwood M, Gaalaas L, Nixdorf DR. Role of MRI for detecting micro cracks in teeth. Journal of Dentomaxillofacial Radiology (July) 2016;45(7):20160150. PMCID:PMC5606261

Pigg M, Law AS, Nguyen RHN, Nixdorf DR, National Dental PBRN Collaborative Group. Validity of preoperative clinical findings to identify dental pulp status: A National Dental PBRN. Journal of Endodontics (June) 2016;42(6):935-942. PMCID:PMC4884138

Shueb SS, Boyer HC, Nixdorf DR. Nonodontogenic ‘tooth pain’ of nose and sinus origin. Journal of the American Dental Association (June) 2016;147(6):457-459. PMID:26762708

Herrero Babiloni AA, Kapos FP, Nixdorf DR. Intraoral administration of botulinum toxin for trigeminal neuropathic pain. Oral Surgery Oral Medicine Oral Pathology Oral Radiology (June) 2016;121(6):e148-e153. PMID:27181448

Nixdorf DR, Law AS, Lindquist K, Reams GS, Cole E, Kanter K, Nguyen RHN, Harris DR, National Dental PBRN Collaborative Group. Frequency, impact, and predictors of persistent pain following root canal treatment: A National Dental PBRN. Pain (January) 2016;157(1):159-165. PMCID:PMC4684798

Moana-Filho EJ, Nixdorf DR, Bereiter DA. Amplified supraspinal processing of dentoalveolar pressure stimuli in atypical odontalgia. Journal Oral & Facial Pain and Headache (Fall) 2015;29(4):349-362. PMCID:PMC4772893

Shueb SS, Nixdorf DR, John MT, Alonso BF, Durham J. What is the impact of acute and chronic orofacial pain on quality of life? Journal of Dentistry (October) 2015;43(10):1203-1210. PMID:26073033

Nixdorf DR, Law AS, John MT, Sobieh RM, Kohli R, Nguyen R, National Dental PBRN Collaborative Group. Diagnoses for Persistent pain following root canal treatment: A nested case series study in the National Dental PBRN. Reprint in Northwest Dentistry (July-August) 2015;94(4):33-40. PMCID:PMC4380676

Nixdorf DR, Law AS, John MT, Sobieh RM, Kohli R, Nguyen R, National Dental PBRN Collaborative Group. Diagnoses for Persistent pain following root canal treatment: A nested case series study in the National Dental PBRN. Journal of Endodontics (April) 2015;41(4):457-463. PMCID:PMC4380676

Law AS, Nixdorf DR, Aguirre AM, Reams GS, Tortomasi AJ, Manne BD, Harris DR, National Dental PBRN Collaborative Group. Predictors of severe pain following root canal therapy in the National Dental PBRN. Journal Dental Research (March) 2015;94(3 Suppl):37S-43S. PMID: 25355775

Durham J, Touger-Decker R, Nixdorf DR, Rigassio-Radler D, Moynihan P. Oro-facial pain and nutrition: a forgotten relationship? Journal of Oral Rehabilitation (January) 2015;42(1):75-80. PMID:25201161

Durham J, Nixdorf DR. Healthcare Pathway and Biopsychosocial Impact of Persistent Dentoalveolar Pain disorder (PDAP): A Qualitative Study. International Endodontic Journal (December) 2014;47(12):1151-1159. PMID:24697333

Law AS, Nixdorf DR, Rabinowitz I, Reams GS, Smith Jr. JA, Torres AV, Harris DR, National Dental PBRN Collaborative Group. Root Canal Therapy Reduces Dimensions of Pain: A National Dental Practice-based Research Network Study. Journal of Endodontics (November) 2014;40(11):1738-1745. PMID:25190605

Edwards PJ, Peterson EJ, Durham J, Nixdorf DR. Methotrexate pharmacotherapy for implant-related temporomandibular joint pain: A case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology (August) 2014;118(2):e44-e47. PMID:25047933

Idiyatullin D, Corum C, Nixdorf DR, Garwood M. Intraoral approach for imaging teeth using the transverse B1 field components of an occlusally oriented loop coil. Magnetic Resonance in Medicine (July) 2014;72(1):160-165. PMID:23900995

Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet J-P, List T, Svensson P, Gonzalez Y, Lobbezoo F, Michelotti A, Brooks S, Ceusters W, Drangsholt M, Ettlin D, Gaul C, Goldberg LJ, Haythornthwaite J, Hollender L, Jensen R, John MT, deLaat A, deLeeuw R, Maixner W, van der Meulen M, Murray GM, Nixdorf DR, Palla S, Petersson A, Pionchon P, Smith B, Visscher C, Zakrzewska J, and Dworkin SF. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. Journal Oral & Facial Pain and Headache (Winter) 2014;28(1):6-27. PMCID:PMC4478082

Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders 3rd edition (beta version). Chapter 13: Painful cranial neuropathies and other facial pains. Cephalalgia (July) 2013;33(9):774-786. PMID:23771276

Durham J, Exley C, John MT, Nixdorf DR. Persistent dentoalveolar pain: The patient’s experience. Journal of Orofacial Pain (Winter) 2013;27(1):6-13. PMID:23424715

Schierz O, Nixdorf DR, Singer S, Reissmann D. Ability to concentrate in patients with painful temporomandibular disorders. Community Dentistry and Oral Epidemiology (December) 2012;40(6):507-515. PMID:22494031

Nixdorf DR, Law AS, Look JO, Rindal DB, Durand EU, Kang W, Agee BS, Fellows JL, Gordan VV, Gilbert GH for The National Dental PBRN Collaborative Group. Large-scale Clinical Endodontic Research in The National Dental Practice-Based Research Network: Study Overview and Methods. Journal of Endodontics (November) 2012;38(11):1470-1478. PMCID:PMC3652657

Schiffman E, Ohrbach R, List T, Anderson G, Jensen R, John MT, Nixdorf D, Goulet JP, Kang W, Truelove E, Clavel A, Fricton J, Look J. Diagnostic criteria for headache attributed to temporomandibular disorders. Cephalalgia (July) 2012:32(9):683-692. PMCID:PMC4521766

Nixdorf DR, Sobieh R, Gierthmühlen J. Using an n-of-1 trial to assist in clinical orofacial pain management. Journal of the American Dental Association (March) 2012;143(3):259-261. PMID:22383206

Nixdorf DR, Drangsholt MT, Ettlin DA, Gaul C, de Leeuw R, Svenson P, Zakrzewska JM, De Laat A, Ceusters A. Classifying orofacial pains: Developing a taxonomy using ontological principles. Journal of Oral Rehabilitation (March) 2012;39(3):161-169. PMCID:PMC3383028

Nixdorf D, Moana-Filho E. Persistent dento-alveolar pain disorder (PDAP): Working towards a better understanding. Reviews in Pain (December) 2011;5(4);18-25. PMCID:PMC4189081

Idiyatullin D, Corum CA, Moeller S, Prasad HS, Garwood M, Nixdorf DR. Dental MRI: Making the Invisible Visible. Journal of Endodontics (June) 2011;37(6):745-752. PMCID:PMC3146019

Anderson GA, John MT, Ohrbach R, Nixdorf DR, Schiffman EL, Truelove ES, List T. Influence of headache frequency on clinical signs and symptoms of TMD in subjects with temple headache and TMD pain. Pain (April) 2011;152(4):765-771. PMCID:PMC3065515

Kobayashi N, Idiyatullin D, Corum C, Moeller S, Chamberlain R, O’Connell R, Nixdorf DR, Garwood M. Detecting fleeting MRI signals with frequency-modulated pulses. AIP Conference Proceedings (March) 2011;1330:23-26. PMCID:PMC3363361

Moana-Filho EJ, Nixdorf DR, John MT, Berieter DA, Harel N. Evaluation of a magnetic resonance-compatible dentoalveolar tactile stimulus device. BMC Neuroscience (October) 2010;11:142. PMCID:PMC2988799

Leppik IE, Goel V, Nixdorf DR, Rarick J, Cloyd JC. Intramuscular and Intravenous Levetiracetam in Humans: Safety and Pharmacokinetics. Epilepsy Research (October) 2010;91(2-3):289-292. PMID:20708904

Nixdorf DR, Moana-Filho EJ, McGuire LA, Hodges JS, Law AS, John MT. Nonodontogenic Pain Post Endodontic Therapy: Meta-analysis. Journal of Endodontics (September) 2010;36(9):224-230. PMCID: PMC2941431

Fricton JR, Ouyanh W, Nixdorf DR, Schiffman ES, Velly AM, Look JO. Critical Appraisal of Methods used in Randomized Controlled Trials of Treatments for Temporomandibular Disorders. Journal of Orofacial Pain (Winter) 2010;24(2):139-151. PMCID:PMC4545283

Nixdorf DR, Moana-Filho EJ, McGuire LA, Hodges JS, Law AS, John MT. Frequency of Persistent Tooth Pain Following Root Canal Therapy: A Systematic Review and Meta-analysis. Journal of Endodontics (February) 2010;36(2):224-230. PMCID: PMC2832800

Law AS, Durand EU, Rindal DB, Nixdorf DR for the DPBRN Group. Doctor, why does my tooth still hurt? Northwest Dentistry (January-February) 2010;89(1):33-36. PMCID:PMC3697825

Nixdorf DR, John MT, Wall MM, Look JO, Fricton JR, Schiffman EL. Psychometric evaluation of the modified Symptom Severity Index (SSI). Journal of Oral Rehabilitation (January) 2010;37(1):11-20. PMCID:PMC2858780

Nixdorf DR, John MT, Schierz O, Bereiter DA, Hellekant G. Self-reported severity of taste disturbances correlates with grade of TMD pain. Journal of Oral Rehabilitation (November) 2009;36(11):792-800. PMCID:PMC3766965

Nixdorf DR, Hemmaty A, John MT, EL Schiffman, Look JO. Electric toothbrush application is a reliability & validity quantitative sensory test in categorizing TMJD patients from controls. BMC Musculoskeletal Disorders (July) 2009;10:94. PMCID:PMC2728093

Giri S, Nixdorf D. Sympathetically Maintained Pain Initially Presenting as TMD and then Parotid Dysfunction. Reprint in Texas Dental Journal (August) 2007;124(8):748-752. PMID:171355808

Giri S, Nixdorf D. Sympathetically Maintained Pain Initially Presenting as TMD and then Parotid Dysfunction. Journal of the Canadian Dental Association (March) 2007;73(2):157-161. PMID:171355808

Alonso AA, Nixdorf DR. Case Series of Four Different Headache Types Presenting as Tooth Pain. Journal of Endodontics (November) 2006;32(11):1110-1113. PMID:17055919

Nixdorf DR, Peters E, Lung KE. Clinical Presentation and differential diagnosis of the nasolabial cyst. Journal of the Canadian Dental Association (March) 2003;69(3):138-141. PMID:12622877

Nixdorf DR, Heo G, Major PD. Controlled trial of botulinum toxin A for chronic myogenous orofacial pain. Pain (October) 2002;99(3):465-473. PMID:12406522

Non Peer-Review Articles

Nixdorf D. The Pain Puzzle: Q’s, A’s, and Mapping the Maze. Northwest Dentistry (July-August) 2015;94(4):25,27-29,31. PMID: 26433992

Nixdorf DR, Kapos FP. Orofacial Pain Diagnoses: How to prepare when seeking a diagnosis for orofacial pain. TNA Quarterly: Facial Pain Association Journal (Summer) 2015;(2):20-25.

Nascimento T, Nixdorf DR. Ways to help reduce pain associated with dental treatment. TNA Alert (Spring) 2010;(1):3-4.

Book Chapters

Herrero Babiloni A, Nixdorf DR. Definition and classification of Orofacial Pains. In: Lavinge GJ (ed). Cohen’s Pathways of the Pulp Expert Consult. 12th edition Wiley: St. Louis. In press.

Law AS, Nixdorf DR, Mattscheck D. Diagnosis of Non-odontogenic Toothache. In: Hargreaves KM, Cohen S (eds). Cohen’s Pathways of the Pulp Expert Consult. 12th edition Mosby: St. Louis. In press.

Kocasarac HD, Geha H, Gaalaas L, Nixdorf DR. Magnetic Resonance Imaging (MRI) for Dental Applications. In: Katkar R K & Geha H (eds). Emerging imaging technology in dento-maxilofacial region. Dental Clinics of North America Elsevier: New York 2018:467-480.

Kapos FP, Nixdorf DR. Diagnosis and Management of Non-odontogenic “Tooth Pain”. In: Ferreira J, Fricton JR, Rhodus N (eds). Orofacial Disorders Springer: New York 2017:197-211.

Friedman S, Azarpazhooh A, Bruder GA, Krell KV, Mello I, Nixdorf DR, Roda RS. AAE Guidelines for the Methodology of Cracked Tooth Studies. Uploaded to AAE website in 2016 https://www.aae.org/uploadedfiles/clinical_resourc...

Mattscheck D, Law AS, Nixdorf DR. Diagnosis of Non-odontogenic Toothache. In: Hargreaves KM, Cohen S (eds). Cohen’s Pathways of the Pulp Expert Consult. 11th edition Mosby: St. Louis 2015:684-705.

Garwood M, Idiyatullin D, Corum CA, Chamberlain R, Moeller S, Kobayashi N, Lehto LJ, Zhang J, O’Connell R, Tesch M, Nissi MJ, Ellermann J, Nixdorf DR. Capturing Signals from Fast Relaxing Spins with Frequency-Swept MRI: SWIFT. In: Young I, Fullerton G, Bydder G (eds) for Imaging of Short T2/T2*. Encyclopedia of Magnetic Resonance. Wiley: New York 2012 DOI: 10.1002/9780470034590.emrstm1259.

Zakrzewska JM, Nixdorf DR. Trigeminal Neuralgia – Definition, Epidemiology, Etiology, Pathogenesis and Management. In: Schmidt RF, Willis WD (eds). Encyclopedia of Pain. Springer-Verlag: New York 2013.

Mattscheck D, Law AS, Nixdorf DR. Diagnosis of Non-odontogenic Toothache. In: Hargreaves KM, Cohen S (eds). Cohen’s Pathways of the Pulp. 10th edition Mosby: St. Louis 2011:49-70.

Nixdorf DR, Velly AM, Alonso AA. Neurovascular pains: Implications of migraine for the oral & maxillofacial surgeon. In: Balasubramaniam R & Klasser GD (eds). Orofacial Pain & Dysfunction. Oral Maxillofacial Surgery Clinic North American 2008;20:221-235.

Nixdorf DR. Trigeminal Neuralgia, Diagnosis & Treatment. In: Schmidt RF, Willis WD (eds). Encyclopedia of Pain. Springer-Verlag: New York 2007:2547-2550.

Nixdorf DR. Management of Non-dental tooth pain. AAOM/AAOP Meeting Proceedings. 2005.

Abstracts

Morrey BR, Idiyatullin D, Gaalaas L, Petersen A, Law A, Barsness B, Royal Mathew, Ordinola-Zapata R, Fok A, Aregawi W, Nixdorf DR. MRI Detection of vertical root fractures in endodontically treated teeth. To be presented at IADR/AADR in Washington, DC; March 2020.

Kim M, Idiyatullin D, Gaalaas L, Nixdorf DR. MRI of fluid flow inside teeth at anatomic velocities. To be presented at IADR/AADR in Washington, DC; March 2020.

Özen AC, Idiyatullin D, Adriany G, Jungst S, Kobayashi N, Morrey B, Garwood M, Nixdorf DR. Design and optimization of an intraoral MRI coil for dental imaging. To be presented at IADR/AADR in Washington, DC; March 2020.

Nisley A, Grande A, Nixdorf DR. Comorbid painful TMD with trigeminal neuralgia and atypical facial pain. To be presented at IADR/AADR in Washington, DC; March 2020.

Morrey BR, Hryvenko I, Nixdorf DR. SUNCT/SUNA: Cases series presenting in an orofacial pain clinic. Presented at IADR/AADR in Vancouver, BC; June 2019.

Shueb SS, Cervantes Chavarri A, Durham J, Nixdorf DR. Identifying criteria for diagnosis of persistent dentolavelar pain disorder and similar conditions: A systematic review. Presented at IADR/AADR in Vancouver, BC; June 2019.

Asadi J, Eriksson L, Nixdorf DR, Vase Toft L, List T, Pigg M. Experimental anesthesia: Exploring active and non-active placebo agents as controls. Presented at IADR/AADR in Vancouver, BC; June 2019.

Sude A, Nixdorf DR. Intractable unilateral headache secondary to facet joint arthropathy. Presented at AAOP in San Diego, CA; May 2019.

Peck CM, Nixdorf DR. Use of Onabotulinum toxin A for the treatment of refractory radiation-induced peripheral neuropathic: A case report. Presented at AAOP in San Diego, CA; May 2019.

Shrivastava M, Ahmad M, Nixdorf DR, Schiffman EL. Relationship between unilateral temporomandibular joint disorders and disc position and degenerative joint changes, a cross-sectional study. Presented at AAOP in San Diego, CA; May 2019.

Mulford K, Lenglet C, Pisharady P, Moen, S, Nixdorf DR, Bharathi J, Grand A, Van de Moortele PF. Toward identifying individual branches in the Trigeminal Nerve with dMRI-based fiber tracking at 7 Tesla: methodological considerations. Presented at ISMRM in Montreal, QC; May 2019.

Herrero Babiloni A, Guay S, Nixdorf DR, De Beaumont L, Lavinge G. Transcranial magnetic stimulation in chronic orofacial pain: a systematic review. Presented at IASP in Boston, MA; September 2018.

Al-Musawi M, Sayeed Z, Colley HE, Murdoch C, Whitworth JM, Stone SJ, Nixdorf DR, Durham J, Valentine RA. In vitro effects of topic neuromodulatory medications on orofacial tissue. Presented at IADR in London UK; July 2018.

Edvinsson O, Ekelun J, Nixdorf DR, Vase Toft L, List T, Pigg, M. Double-blind concealment inadequate for local anesthesia administration studies using normal saline control. Presented at IADR in London UK; July 2018.

Hryvenko I, Nixdorf DR, Nguyen RH, Law AS, National Dental PBRN Collaborative Group. Long-term outcome of patients with persistent pain following root canal treatment: NDPBRN. Presented at AAOP in Chicago, IL; April 2018.

Sude A, Hryvenko, I, Schrock L, Nixdorf DR. Prevalence and clinical characteristics of oromandibular dystonia in an orofacial pain clinic: a descriptive study. Presented at AAOP in Chicago, IL; April 2018.

Nguyen RHN, Nixdorf DR, Law AS, Lam EWN, Koratkar H, Nosrat A, Fellows J, National Dental PBRN Collaborative Group. Predictors of severe pain following root canal treatment: National-Dental-PBRN. Presented at AADR in Fort Lauderdale, FL; March 2018.

Law AS, Royal MJ, Nixdorf DR, Lam EWN, Fellows J, Nguyen RHN, National Dental PBRN Collaborative Group. Anatomy, findings, and procedure characteristics within the PREDICT Study: National-Dental-PBRN. Presented at AADR in Fort Lauderdale, FL; March 2018.

Nixdorf DR, Law AS, Lam EWN, Fellows J, Hguyen RHN, National Dental PBRN Collaborative Group. Patient, pain-related, and psychosocial characteristics within the PREDICT Study: National-Dental-PBRN. Presented at AADR in Fort Lauderdale, FL; March 2018.

Fellows JL, Law AS, Basile SV, Mills JR, Lindquist K, Rauschenberger CR, Poppleton K, Hguyen RHN, Nixdorf DR, Cochran DL, Lindauer PA, Tasgaonkar N, Lam EWN, National Dental PBRN Collaborative Group. Post-endodontic pain and health-related quality of life: A National Dental Practice-Based Research Network Study. Presented at AADR in Fort Lauderdale, FL; March 2018.

Kim M, Idiyatullin D, Gaalaas L, Hilton J, Nixdorf DR. MRI of fluid flow inside teeth using custom head phantom. Presented at AADR in Fort Lauderdale, FL; March 2018.

Cervantes AR, Shueb SS, Nixdorf DR. Persistent dentoalveolar pain disorder, the patient profile: A systematic review. Presented at AAOP in Scottsdale, AZ; May 2017.

Schuurmans TJ, Nixdorf DR, Idiyatullin D, Law AS, Barsness BD, Roach SH, Gaalaas L. Accuracy and reliability of root crack and fracture detection in teeth using Sweep Imaging with Fourier Transform (SWIFT) magnetic resonance imaging (MRI). Presented at AAE in New Orleans, LA; April 2017.

Nguyen RHN, Law AS, Nixdorf DR, National Dental PBRN Collaborative Group. Predictors of acute and persistent pain following RCT: National Dental-PBRN. Presented at IADR/AADR in San Francisco, CA; March 2017.

Hryvenko I, Nixdorf DR, Nguyen RHN, Law AS, National Dental PBRN Collaborative Group. Long-term outcome of patients with persistent pain following RCT: National Dental-PBRN. Presented at IADR/AADR in San Francisco, CA; March 2017.

Kim M, Idiyatullin D, Gaalaas L, Hilton J, Nixdorf DR. Magnetic resonance imaging of flow within pulp of extracted tooth. Presented at IADR/AADR in San Francisco, CA; March 2017.

Pigg M, Nixdorf DR, Nguyen RHN, Law AS, National Dental PBRN Collaborative Group. Distinguishing pulpal pain from periapical pain: National Dental-PBRN. Presented at IADR in Seoul, South Korea; June 2016.

Moana-Filho EJ, Nixdorf DR, Bereiter DA, Lenglet C. Probing human orofacial-related brain pathways in vivo. Presented at IADR in Seoul, South Korea; June 2016.

Al-Musawi M, Durham J, Whitworth JM, Stone SJ, Nixdorf DR, Valentine RA. Is Amitriptyline safe as topical treatment for neuropathic orofacial pain? Presented at IADR in Seoul, South Korea; June 2016.

Nixdorf DR, Stone SJ, Robinson LJ, Durham J. Initial assessment of the Persistent Dentoalevolar Pain Disorder screening instrument. Presented at IADR in Seoul, South Korea; June 2016.

Herrero Babiloni A, Nixdorf DR, Law AS, Moana-Filho EJ, Durham J. Assessing the Modified S-LANSS for Detecting Neuropathic Orofacial Pain Conditions: a cross-sectional study. Presented at AAOP meeting in Orlando, FL; April 2016.

Idiyatullin D, Garwood M, Nixdorf DR. Dental MRI can detect micro-cracks. Presented at ISMRM in Toronto, ON; May 2015.

Law AS, Nixdorf DR, Sobieh RM, Kohli R, John MT, and the National Dental PBRN Collaborative Group. Diagnoses for pain present 6 months following root canal therapy. Presented at IADR in Cape Town, South Africa; June 2014.

Fonseca Alonso B, Durham J, John MT, Law AS, Nixdorf DR. Distinguishing odonotogenic pain from TMD using screening instruments. Presented at IADR in Cape Town, South Africa; June 2014.

Shueb SS, Nixdorf DR, Durham J, John MT. Four groups of orofacial pain patients have similar impairment in oral health quality of life. Presented at AAOP in Las Vegas, LV; May 2014.

Mittal H, John MT, Nixdorf DR. Unconventional treatment course for persistent dento-alveolar pain: A case report. Presented at AAOP in Las Vegas, LV; May 2014.

Idiyatullin D, Corum CA, Nixdorf DR, Garwood M. Intraoral approach for imaging teeth using the transverse B1 field components of an occlusally oriented loop coil. Presented at ISMRM in Milan, Italy; May 2014.

Sun Y, Idiyatullin D, Brauckmann O, Nixdorf DR, Kentgens A, Garwood M, Heerschap A. 31P MRI of human teeth with Nuclear Overhauser Effect enhancement. Presented at ISMRM in Milan, Italy; May 2014.

Goerke U, Kersten ME, Bachani S, Bereiter DA, Nixdorf DR. Mapping Activation in the Human Brainstem at 7 T with High Spatial and Temporal Resolution Using RASER and SSBA. Presented at ISMRM in Milan, Italy; May 2014.

Fonseca Alonso B, Durham J, John MT, Law AS, Nixdorf DR. Assessment of a questionnaire’s ability to differentiate odontogenic pain form TMD-related pain. Presented at AAOP in Orlando, FL; April 2013.

Shueb SS, Boyer H, Nixdorf DR. Nonodeontogenic “tooth” pain related to the nose and sinus. Presented at AAOP in Orlando, FL; April 2013.

Idiyatullin D, Corum C, Nixdorf DR, Garwood M. Intraoral RF loop coil in the occlusal plan, orthogonal to B0, for dental imaging. Presented at ISMRM in Salt Lake City, UT; April 2013.

Kersten ME, Breitenfeldt CL, Goerke U, Hodges JS, Bereiter DA, Nixdorf DR. Temporal summation of gingival pain in humans. Presented at IADR in Seattle, WA; March 2013.

Nixdorf DR, Look JO, Law AS, Reams GJ, Smith JA, Sørensen LH, Torres AV, Chen R, Kim Y for the National Dental PBRN Collaborative Group. Predicting persistent pain following endodontic treatment within The National-Dental-PBRN. Presented at IADR in Seattle, WA; March 2013.

Law AS, Nixdorf DR, Look JO, Reams GJ, Smith JA, Sørensen LH, Torres AV for the National Dental PBRN Collaborative Group. Frequency of persistent pain following endodontics within the National-Dental-PBRN. Presented at IADR in Seattle, WA; March 2013.

Nixdorf DR, Rabinowitz I, Law AS, Smith JA, Reams GJ, Sørensen LH, Torres AV, Look JO for the National Dental PBRN Collaborative Group. Impact of persistent pain following endodontics within The National-Dental PBRN. Presented at IADR in Seattle, WA; March 2013.

Leon-Salazar V, Beiraghi S, Larson BE, Nixdorf DR, Idiyatullin D, Zhang J, Garwood M. Use of SWIFT MRI for Visualization of the Crainofacial Skeleton. Presented at IADR in Seattle, WA; March 2013.

Kersten ME, Nixdorf DR, Goerke U, Bereiter DA. Temporal summation of intraoral pressure-pain using a modified MRI-compatible device. Presented at IADR in Iguaçu Fall, Brazil; June 2012.

Law AS, Nixdorf DR, Look JO, Rindal DB, DURAND EC, KANG W, Gordan VV, FELLOWS JL, Gilbert GH and The DPBRN Collaborative Group. Feasibility of conducting large-scale endodontic research within The Dental PBRN. Presented at IADR in Iguaçu Fall, Brazil; June 2012.

Rabinowitz I, Nixdorf DR, Look JO, Rindal DB, Gordan VV, Gilbert GH, Law AS and The DPBRN Collaborative Group. Peri-operative endodontic pain within The Dental Practice-Based Research Network. Presented at IADR in Iguaçu Fall, Brazil; June 2012.

Durham J, Exley C, John M, Nixdorf DR. Characterising the pain, understanding the impacts, of persistent dentoalveolar pain. Presented at IADR in Iguaçu Fall, Brazil; June 2012.

Fonseca Alonso B, Nixdorf DR. Cerebral palsy-related masticatory muscle pain treatment using botulinum toxin Type B following secondary non-response: A case report. Presented at SEDCYDO in Valencia, Spain; May 17-20, 2012.

Rener-Sitar K, Nixdorf DR, Mulet-Pradera M, Schiffman EL, John MT. How Relevant are Existing Oral Health-Related Quality of Life Instruments for TMD Patients? Presented at AAOP in Las Vegas, NV; April 28-May 1, 2011.

Nixdorf DR, Jones RS, Leon-Salazar V, John MT, Idiyatullin D. Detecting early carious lesions: An ex-vivo MRI-based study. Presented at IADR in San Diego, CA; March 2011.

Idiyatullin D, Corum C, Moeller S, Garwood M, Nixdorf DR. SWIFT, a new method for MRI in dentistry. Presented at IADR in San Diego, CA; March 2011.

Moana-Filho E, Bereiter DA, Nixdorf DR. fMRI-measured brain activation evoked by dentoalveolar pressure in Atypical Odontalgia. Presented at IADR in San Diego, CA; March 2011.

Alonso AA, Hodges JS, Durand S, Leon-Salazar V, John MT, Nixdorf DR. Intraoral quantitative sensory testing: Accounting for observer variability. Presented at IADR in San Diego, CA; March 2011.

Nixdorf DR, Schiffman EL, Ohrbach R, List T, John MT, Anderson G, Look JO. Proposed revision of the ICHD-II criteria for headache or facial pain attributed to temporomandibular joint (TMJ) disorders. Presented at IASP in Montreal, PQ; September 2010.

Nixdorf DR, Moana EJ, John MT, Berieter DA, Harel N. Differences in central pain processing in patients with Atypical Odontalgia and match pain-free controls. Presented at Pain Imaging satellite meeting of IASP in Quebec City, PQ; August 2010.

Moana EJ, Nixdorf DR, John MT, Berieter DA, Harel N. Development and testing of MRI-compatible intraoral device for somatosensory stimulation. Presented at IADR in Barcelona, Spain; July 2010.

Schierz O, Nixdorf DR, Reissmann DR. Correlation of self-reported ability to concentrate and correlation with severity of chronic TMD pain. Presented at IADR in Barcelona, Spain; July 2010.

Idiyatullin D, Corum C, Moeller S, Prasad H, Garwood M, Nixdorf DR. SWIFT verses x-ray in dental imaging. Presented at ISMRM meeting in Stockholm, Sweden; May 2010.

Nixdorf DR, John MT, Schierz O, Hellekant G. Self-reported severity of taste disturbances correlates with severity of TMD pain. Presented at Neuropathic Pain SIG satellite meeting in London, UK; August 2008.

Nixdorf DR, John MT, Wall MM, Fricton JR. Jaw and temple pain as distinct components within TMD pain. Presented at IADR meeting in Toronto, ON; July 2008.

.Moana Filho EJ, Nixdorf DR, John MT, McGuire LA, Law AS. Meta-analysis assessing persistent pain following root canal therapies. Presented at IADR meeting in Toronto, ON; July 2008.

Sobieh R, Nixdorf DR. Use of N-of-1 Trials in the Clinical Care of Orofacial Pain. Presented at AAOP meeting in Los Angeles, CA; April 2008.

Moana Filho EJ, Nixdorf DR. Neuralgia Case Series: Trigeminal, Nervus Intermedius & Glossopharyngeal Neuralgia Cases Interpreted as TMD. Presented at AAOP meeting in Los Angeles, CA; April 2008.

Nixdorf DR, John MT, Wall MM, Schiffman EL. Psychometric evaluation of the modified Symptom Severity Index (SSI). Presented at IADR meeting in Toronto, ON; July 2008 J Dent Res 87(Spec Iss A);101029:2008.

Decker K, John MT, Nixdorf DR, Schiffman EL. Characteristic mouth opening: a precise measurement of vertical mandibular movements. Presented at IADR meeting in Toronto, ON; July 2008 J Dent Res 87(Spec Iss A):2008.

Nixdorf DR, Drangsholt M, Law AS, Rindal DB, Velly AM, Richman, JS Williams OD. Persistent pain associated with root canal therapy. Presented at ACRT meeting in Washington, DC; March 2008.

Leppik IE, Rarick JO, Nixdorf DR, Goel V, Cloyd JC. Tolerability and safety of IM Levetiracetam in humans. Presented at AES meeting in Philadelphia, PA; December 2007.

Hemmaty A, Nixdorf DR, John MT, Look JO, Schiffman EL. Reliability and comparison of 3 tactile quantitative neurosensory tests in TMD patients without wide-spread pain. Presented at IADR meeting in New Orleans, LA; March 2007 J Dent Res 86(Spec Iss A):2007.

Giridharagopalan S, Nixdorf DR. Sympathetically involved pain initially presenting as TMD and then Parotiditis. Presented at AAOP & AAOM meeting in Phoenix, AZ; April 2005.

Alonso AA, Nixdorf DR. Case series of four different headaches presenting as tooth pain. Presented at AAOP & AAOM in Phoenix, AZ; April 2005.

MacMenanin L, Nixdorf DR, Rake S, Rake PA. Sevoflurane for office-based pediatric general anesthesia. Presented at AAOMS meeting in San Francisco, CA; September 2004.

Nixdorf DR, Heo G, Major PD. Controlled trial of botulinum toxin A for chronic myogenous orofacial pain. Presented at IASP meeting in San Diego, CA; August 2002.

Peters E, Yu D, Yu H, Nixdorf D. Localized endodontic associated exostosis. Presented at AAOMP meeting in New Orleans, LA; April 2002.

Sasvari D, Peters E, Bagnall K, Nixdorf DR. Non-specific radicular pulp calcifications associated with odontalgia. Presented at IAOP meeting in Guatemala City, Guatemala; September 2000.

Nixdorf DR, Osborn JW. Normal human bite force direction. Presented at Biannual Prairie Province Research meeting in Saskatoon, SK; October 1993.

Table Clinics

Sakhi E, Nixdorf DR, Beiraghi S. The effect of adding chloral hydrate to meperidine and hydroxyzine oral sedation. Presented at AAPD meeting in San Francisco, CA; May 2004.

Nixdorf DR, Weed HG. Is preoperative testing of coagulation & anticonvulsants necessary? Presented at Post College Assembly in Columbus, OH; April 1998.

Nixdorf DR, Osborn JW. Normal Human Bite Force Direction. Presented at CDA meeting in Ottawa, ON; September 1995.

Letters & Commentaries

Nixdorf DR. BTX-A for persistent myofascial TMD pain: Interpreting a small clinical trial with negative results. Pain (September) 2011;152(9):1944-1945. PMID: 21641114

Bereiter DA, Okamoto K, Tashiro A, Nixdorf DR. A comment on experimental occlusal interference induces long-term masticatory muscle hyperalgesia in rats by Cao et al. Pain (March) 2010;148(3):519; author reply 519-20. PMID: 20116926

Videos

Nixdorf DR, Nasseh AA. Differential diagnosis of persistent pain after toot canal treatment. Uploaded in April 9, 2015 https://www.youtube.com/watch?v=tmspxYsJq7s

Nixdorf DR, Knaup D. Peri-operative pain and root canal therapy. Uploaded in May 24, 2014

https://www.youtube.com/watch?v=5qprFS9hkks&list=P...

Dr. Nixdorf’s teaching interests align with his clinical interests, namely the diagnosis and management of chronic ororfacial pains. Specifically he lectures on the differential diagnosis of orofacial pains, classification of orofacial pain, and treatment approaches to orofacial pain management.

Past activities

Lecturing:

- Director: DDS 6271 “Temporomandibular Disorders & Orofacial Pain” (1 credit) from 2004 to 2013

- DDS 6215 “Pharmacology” – 2 lectures (Director: Leonard Lichtblau & Carolyn Fairbanks) from 2003 to 2013 (note, was a different course number and director from 2003 to 2011). Topics covered = Clinical use of local anesthetics; Pharmacotherapy for pain management

- NSC 8221 “Neuroscience of Pain and Analgesia” – 1 lecture (Director: Chris Honda)⁺ Topics covered = Imaging pain in humans

- KI-UMN “Pain Mechanisms: From Molecules to Treatment” – 1 lecture (Director: George Wilcox) ⁺ Topics covered = Headache and TMD

⁺ these courses are given every other year

Yearly activities

Lecturing:

Undergraduate Students (Dentistry)

- DDS 6151 “Pain & Anxiety Management” – 2 lectures (Director: Rachel Uppgaard) Topics covered = Conceptualizing the approach to pain control in dentistry, central sensitization

- DDS 6169 “Occlusion” – 1 lecture (Director: John Beyers) Topic covered = Muscular and neural control of occlusion

- DDS 6271 “Temporomandibular Disorders & Orofacial Pain” – 4 lectures (Director: Shanti Kaimal) Topics covered = Headaches; Neuropathic orofacial pains; Poor prognosis; Course review

Graduate Students

- DENT 8121 “Literature Review in TMD/OFP” – 16 lectures (Director: Donald Nixdorf) Topics covered = Various articles

- TMJP 8440 “Summer Overview Course in TMD/OFP” – 2 lectures (Director: Mariona Mulet) Topics covered = Research overview on persistent dentoalveolar pain

- TMJP 8441 “Seminars in TMD & Orofacial Pain” – 4 lectures (Director: Mariona Mulet) Topics covered = Neurological evaluation; Neurological testing; Diagnosis and treatment of CRPS; Diagnostic blocks of the head and neck

- DENT 8120 “Advance Theory and Principles of TMD” – 7 lectures (Director: Estephan Moana) Topics covered = Headache diagnosis, pathophysiology, and management; Pharmacotherapy for chronic TMD; Neuropathic pain, CRPS

- DENT 8123 “Advanced Topics in TMD/OFP” – 2 lectures (Director: Mariona Mulet) Topics covered = Central representation of pain; Pharmacotherapy for neuropathic pains Organize Basic Science and Pharmacology block – 14 lectures

- PUBH 6301 “Fundamentals of Clinical Research” – 1 lecture (Directors: Russell Luepker & Kamakshi Lakshminarayan) Topics covered = Practice-Based Research Networks

Clinical:

- DDS 6626 “TMD/OFP Clinical Practice” – elective rotation of 4^th year dental students one day per week

- TMJP 8442 “TMD/OFP Clinical Practice” – resident education one day per week

Mock Boards:

- organize and participate as an oral and written examiner at UMN (1 day)

Thesis Examination:

2015 Ph.D. candidate Nadine I. Khawaja at King’s College London, Cerebral blood flow imaging of acute post-operative pain and analgesic response following third molar surgery

• Diplomate, American Dental Society of Anesthesiology (ADSA) 2004
• Diplomate, American Board of Orofacial Pain (ABOP) 2002

Dr. Nixdorf’s clinical interests include the diagnosis and management of chronic ororfacial pains. This includes TMD pain and jaw dysfunction; neuropathic orofacial pains, such as trigeminal neuralgia and deafferentation pain (a.k.a atypical odontalgia); Headache management, including tension-type, migraine, paroxysmal hemicrania, cluster and other autonomic cephalalgias.